Retinitis Pigmentosa (RP) is a group of inherited, progressive, retinal degenerative diseases. In Spain, 15.000 people are affected by RP and 480.000 have one or more of the different genes responsibles for the disease. RP is the major cause of blindness in young adults and there is no treatment or therapy. Then, research in this field is essential.
RP shows different genotypes and phenotypes and the visual outcome varies between different subtypes as well as between members of the same family. The most complete knowledge about the morphological and functional alterations of the retina of RP patients is essential to select for each RP patient the most suitable regenerative therapy from those now under research.
The aim of the investigation is precisely to study, with the most advanced morphological and functional now available techniques, the retina of RP patients and to classify them according to their alterations.
The specific objectives of our research are: